Product Description

B4GALNT1/GM2 synthase Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65734-50, BS65734-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: Q00973

Host: Rabbit

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

Applications: WB, IHC-P

All Applications: WB=1:500-2000，IHC-P=1:100-500

Background: GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: B4GALNT1/GM2 synthase Polyclonal Antibody detects endogenous levels of B4GALNT1/GM2 synthase protein.

Bioworld Molecular Weight: 59 kD，53 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti- B4GALNT1/GM2 synthase at 1/1000 dilution, Primary: Anti- B4GALNT1/GM2 synthase at 1/1000 dilution, Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (B4GALNT1) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C

Alternative Name: (N acetylneuraminyl) galactosylglucosylceramide; (N-acetylneuraminyl)-galactosylglucosylceramide; 4 N-acetylgalactosaminyltransferase 1; 4933429D13Rik; B4GALNT1; B4GN1_HUMAN; Beta 1 4 N acetyl galactosaminyl transferase 1; Beta 1 4 N acetylgalactosaminyltransferase 1; Beta-1; BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE 1; BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE; Beta1 4GalNAc T; Gal-NAc-T; GALGT; Galgt1; GalNAc T; GalNAc-T; GALNACT; GD2 synthase; Ggm-2; Ggm2; GM2 synthase; GM2/GD2 synthase; SIAT 2; SIAT2; UDP Gal:betaGlcNAc beta 1 4 N acetylgalactosaminyltransferase transferase 1; UDP N acetyl alpha D galactosamine:(N acetylneuraminyl).  

Immunogen: KLH conjugated synthetic peptide derived from human B4GALNT1/GM2 synthase:451-533/533 

Conjugate: Unconjugated

Modification: Unmodified