B4GT7 rabbit pAb - ES9450

B4GT7 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES9450-50, ES9450-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the beta-1, 4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1, 3-Gal-beta1, 3-Gal-beta1, 4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. M

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 35kD

Human Gene ID: 11285

Human SWISS Prot NO: Q9UBV7

Subcellular Location: Golgi apparatus Golgi stack membrane; Single-pass type II membrane protein. Cis cisternae of Golgi stack.

Research Use Only