BACE Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22286-50, RA22286-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: beta-secretase 1 (BACE1) Homo sapiens This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, ELISA Alternate Names: Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2) Clonality: Polyclonal Dilution: WB 1:500-2000, ELISA 1:10000-20000 Molecular Weight: 55 Protein Molecular Weight (kDa): 55 Storage: -20°C/1 year Human Gene ID: 23621 Human SwissProt Number: P56817 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only