BACE1 Monoclonal Antibody-MB10603

BACE1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10603-50, MB10603-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P56818

Host: Rabbit

Reactivity: Rat

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of BACE1 in rat BrainLysates using BACE1 antibody.

Bioworld Molecular Weight: Calculated MW: 56 kDa; Observed MW: 70 kDa

Specificity: IgG

Alternative Name: ASP2; Bace; C76936

Immunogen: Recombinant protein of mouse BACE1

Conjugate: Unconjugated

Modification: Unmodified