Product Description

BACH1 (L160) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS1868-50, BS1868-100

Sizes: 50µl, 100µl

Swiss-Prot: O14867

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

Background: BACH1 and BACH2, heterodimerization partners of MafK, are members of a novel family of BTB/POZ-basic region leucine zipper (bzip) factors. BACH1 and BACH2 have significant similarity to each other in BTB domain and Cap‘n’ collar-type bZip domain but are otherwise divergent. BACH1 appears ubiquitous, whereas BACH2 is restricted to monocytes, neuronal cells and is abundantly expressed in the early stages of B-cell differentiation. BACH2, a 841 amino acid polypeptide, is an Nrf2-related transcription repressor and a tissue-specific partner of the Maf oncoprotein family.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: BACH1 (L160) polyclonal antibody detects endogenous levels of BACH1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of IKBKG pAb at 1:500 dilution
Lane 1: The lung tissue lysate of Mouse (40ug)
Lane 2: Aml-12 whole cell lysate (40ug)
Lane 3: PMVEC whole cell lysate (40ug)
Lane 4: HEK293T whole cell lysate (40ug)
Lane 5: Hela whole cell lysate (40ug)
Lane 6: SHSY5Y whole cell lysate (40ug) , Immunohistochemistry (IHC) analyzes of BACH1 (L160) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.showing Nucleus staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Bioworld Molecular Weight: ~ 90 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Transcription regulator protein BACH1; BTB and CNC homolog 1; HA2303; BACH1

Immunogen: Synthetic peptide, corresponding to amino acids 131-180 of Human BACH1.

Conjugate: Unconjugated

Modification: Unmodified