BAK1 Polyclonal Antibody - E-AB-60009

BAK1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60009-60, E-AB-60009-120, E-AB-60009-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: BAK1

Target Synonym: BAK1; BAK; BAK-LIKE; BCL2L7

Research Areas: Cancer, Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q16611

Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human BAK1 (NP_001179.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Calculated MW: 16kDa/23kDa

Observed MW: 26kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only