BAM32 (phospho Tyr139) rabbit pAb - ES5538

BAM32 (phospho Tyr139) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5538-50, ES5538-100

Citations, Manuals and MSDS Available upon request.

Background: function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K., induction:Upon B-cell activation., PTM:Phosphorylated on tyrosine residues., similarity:Contains 1 PH domain., similarity:Contains 1 SH2 domain., subcellular location:Membrane-associated after cell stimulation leading to its translocation., subunit:Interacts with PtdIns (3, 4, 5)P3 and PLCG2. In vitro, interacts with PtdIns (3, 4)P2., tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,

Alternate Name: DAPP1; BAM32; HSPC066; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; hDAPP1; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human DAPP1 around the phosphorylation site of Tyr139. AA range:105-154

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 32kD

Human Gene ID: 27071

Human SWISS Prot NO: Q9UN19

Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Membrane-associated after cell stimulation leading to its translocation.

Research Use Only