BANF1 Polyclonal Antibody-BS90118

BANF1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90118-50, BS90118-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O75531(Human) O54962(Mouse) Q9R1T1(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC IHC FC

All Applications: WB:1:500
ICC:1:50-1:100
IHC:1:50-1:200
FC:1:50-1:100

Background: Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: BANF1 polyclonal antibody detects endogenous levels of BANF1 protein.

Bioworld Molecular Weight: 10 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining BANF1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti-BANF1 antibody. Counter stained with hematoxylin.

Alternative Name: BANF1, BAF, BCRG1, BAF, BAF, BANF 1, BANF1, Barrier to autointegration factor 1, Barrier to autointegration factor, Barrier-to-autointegration factor, BCRG 1, BCRG1, BCRP 1, BCRP1, Breakpoint cluster region protein 1, D14S1460, MGC111161, NGPS,

Immunogen: Full length recombinant protein of human BANF1.

Conjugate: Unconjugated

Modification: Unmodified