Product Description

BAP1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11928-50, MB11928-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q92560

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of BAP1 in Hela, A549, HL-60, U2OSLysates using BAP1 antibody.

Bioworld Molecular Weight: Calculated MW: 80 kDa; Observed MW: 95 kDa

Specificity: IgG

Alternative Name: UCHL2; hucep-6; HUCEP-13

Immunogen: Recombinant protein of human BAP1

Conjugate: Unconjugated

Modification: Unmodified