Product Description

BAX Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-22128-60, E-AB-22128-120, E-AB-22128-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: BAX

Target Synonym: Apoptosis regulator BAX; BAX; Bax-protein; BAX; BAXA; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; Bcl-2-like protein 4; BCL2 associated X protein; BCL2 associated X protein omega; BCL2 associated X protein transcript variant delta2; Bcl2-L-4; BCL2L4; membrane isoform alpha

Research Areas: Cancer, Cell Biology, Metabolism

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone No.: Clone:1D8

UNIProt ID: Q07812

Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide of Bax

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification Method: Protein A purification

Dilution: WB 1:1000-2000, IHC 1:100-200

Observed MW: 20kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only