Product Description

BAX Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66572-50, MB66572-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Bax is a key component for cellμlar induced apoptosis through mitochondrial stress. Upon apoptotic stimμlation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9, and initiation of the caspase activation pathway for apoptosis.

Category: Primary Antibody

Reactivity: Human, Monkey

Host: Mouse

Applications: WB

Alternate Names: BCL2L4, Apoptosis regμlator BAX, Bcl-2-like protein 4, Bcl2-L-4

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Purified recombinant human Bax protein fragments expressed in E.coli

Dilution: WB (1/500 - 1/1000)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of BAX protein.

Molecular Weight: ~ 20 kDa

Pathway: Regμlation of Apoptosis，Mitochondrial Control of Apoptosis，Inhibition of Apoptosis，PI3K AKT signaling，SAPK JNK Signaling Cascades，Warburg Effect

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q07812

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only