Product Description

Bax Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA10829-50, RA10829-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.

Reactivity: Human, Monkey

Host: Mouse

Applications: WB

Alternate Names: Apoptosis regulator BAX, Apoptosis regulator BAX cytoplasmic isoform beta, Apoptosis regulator BAX membrane isoform alpha, BAX, Bax isoform psi, BAX protein cytoplasmic isoform delta, Bax protein cytoplasmic isoform delta., Bax protein cytoplasmic isoform gamma, Bax zeta, Bax-protein, BAX_HUMAN, BAXA, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, Bcl2-L-4, BCL2L4, membrane isoform alpha.

Clonality: Monoclonal

Dilution: wb dilution 1:1000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 581

Protein Molecular Weight（KDa): 20

Molecular Weight: 20

Research Use Only