Product Description

BBS1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65686-50, BS65686-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep

Host: Rabbit

Applications: WB, IHC-P

Alternate Names: AI451249, Bardet-Biedl syndrome 1, Bardet-Biedl syndrome 1 homolog, Bardet-Biedl syndrome 1 protein, BBS1, BBS1_HUMAN, BBS2-like protein 2, D19Ertd609e.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human BBS5

Dilution: WB=1:500-2000 IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: BBS1 Polyclonal Antibody detects endogenous levels of BBS1 protein.

Molecular Weight: 65 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8NFJ9

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only