BCAS4 Polyclonal Antibody - E-AB-16277

BCAS4 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16277-60, E-AB-16277-120, E-AB-16277-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: BCAS4

Target Synonym: BCAS4; BCAS4/BCAS3 fusion; BCAS4; Breast carcinoma amplified sequence 4; Breast carcinoma amplified sequence 4/3 fusion protein; Breast carcinoma-amplified sequence 4; CNOL; FLJ20495; RP5-1071L10.2

Research Areas: Cancer

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8TDM0

Background: The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer.The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells. Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human BCAS4

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW: 23kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only