Bcl-2 (phospho Ser70) rabbit pAb - ES1272

Bcl-2 (phospho Ser70) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1272-50, ES1272-100

Citations, Manuals and MSDS Available upon request.

Background: BCL2, apoptosis regulator (BCL2) Homo sapiens This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

Alternate Name: BCL2; Apoptosis regulator Bcl-2

Source: Rabbit

Applications: WB; IHC; IF; IP; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human BCL-2 around the phosphorylation site of Ser70. AA range:41-90

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 26kD

Human Gene ID: 596

Human SWISS Prot NO: P10415

Subcellular Location: Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm.

Research Use Only