Bcl-7a Polyclonal Antibody - BT-AP00869

Bcl-7a Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00869-20, BT-AP00869-50, BT-AP00869-100

Citations, Manuals and MSDS Available upon request.

Background: BCL7A (BCL tumor suppressor 7A) is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for BCL7A.

Research Areas: Cell Biology

Target Protein: BCL7A

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Bcl-7a Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 22810

UniProt Accession: Human: Q4VC05; Mouse: Q9CXE2

Synonyms: BCL7A; B-cell CLL/lymphoma 7 protein family member A

GeneID: Human: 605; Mouse: 77045

Research Use Only