Product Description

Bcl10 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS48501-50, BS48501-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regμlators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregμlation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing resμlts in mμltiple transcript variants. [provided by RefSeq, Mar 2016]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF, FC, IP

Alternate Names: CLAP, mE10, CIPER, IMD37, c-E10, CARMEN

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human Bcl10

Dilution: WB: 1:1000 IHC: 1:100 ICC/IF: 1:100 FC: 1:50 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 26 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O95999

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only