Product Description

BEND4 Polyclonal Antibody

Catalogue Numbers: BS67239-50, BS67239-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q6ZU67

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: BEND4 is a 530 amino acid protein that contains a BEN domain. BEND4 exists as five alternatively spiced isoforms and is considered a complete proteome. BEN domain mediates protein–DNA and protein–protein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND4 gene maps to human chromosome 4p13. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 200% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of BEND4 protein.

Extra Notes: Western blot analysis of BEND4 expression in SGC7901 (A), EC9706 (B), mouse liver (C) whole cell lysates.

Bioworld Molecular Weight: ~ 58, 46 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: CCDC4; BEN domain-containing protein 4; Coiled-coil domain-containing protein 4

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BEND4. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified