beta Arrestin 1 (6A1) Monoclonal Antibody-MB3022

beta Arrestin 1 (6A1) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3022-50, MB3022-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P49407

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of betaArrestin 1 in K562 and HelaLysates using betaArrestin 1 antibody.

Bioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 51 kDa

Specificity: IgG2b

Alternative Name: ARB1; ARR1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.

Immunogen: Recombinant human β-Arrestin 1 protein.

Conjugate: Unconjugated

Modification: Unmodified