Product Description

Beta-tubμlin Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65889-50, MB65889-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Tubμlin is the major constituent of microtubμles. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and maintenance. Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubμles and thereby lead to increased microtubμle dynamics and axon repμlsion (PubMed:28483977). Plays a role in dorsal root ganglion axon projection towards the spinal cord (PubMed:28483977).

Category: Primary Antibody

Reactivity: Zebrafish

Host: Mouse

Applications: WB

Alternate Names: TUBB4, Tubμlin beta-3 chain, Tubμlin beta-4 chain, Tubμlin beta-III

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence of zebrafish Beta-tubμlin. The exact sequence is proprietary.

Dilution: WB (1/2000 - 1/5000)

Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Beta-tubμlin protein.

Molecular Weight: ~ 55 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only