BEX3 rabbit pAb - ES11172

BEX3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11172-50, ES11172-100

Citations, Manuals and MSDS Available upon request.

Background: domain:The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR., function:May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases., miscellaneous:Binds transition metals., PTM:Ubiquitinated. Degraded by the proteasome., similarity:Belongs to the BEX family., subcellular location:Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria., subunit:Self-associates. Interacts with 14-3-3 epsilon (YWHAE). Interacts with DIABLO/SMAC (By similarity). Binds to the DEATH domain of p75NTR/NGFR., tissue specificity:Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 1-80

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 12kD

Human Gene ID: 27018

Human SWISS Prot NO: Q00994

Subcellular Location: Nucleus. Cytoplasm. Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity).

Research Use Only