BHMT2 Polyclonal Antibody - E-AB-52473

BHMT2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-52473-60, E-AB-52473-120, E-AB-52473-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: BHMT2

Target Synonym: Betaine homocysteine methyltransferase 2; Betaine homocysteine S methyltransferase 2; EC 2.1.1.5; FLJ20001 ; S methylmethionine homocysteine S methyltransferase BHMT2; SMM hcy methyltransferase

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9H2M3

Background: Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human BHMT2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Calculated MW: 40 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only