Bim (phospho-Ser77) Rabbit Polyclonal Antibody - RA22404

Bim (phospho-Ser77) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22404-50, RA22404-100

Citations, Manuals and MSDS Available upon request.

Background: BCL2 like 11 (BCL2L11) Homo sapiens The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3) . It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 10018

Protein MW (KDa): 22

SWISS: O43521

Source: Rabbit

Research Use Only