Biotin Anti-Human CD32 Antibody [IV-3] - E-AB-F1075B

Biotin Anti-Human CD32 Antibody [IV-3]

Size: 100μg

Catalogue Number: E-AB-F1075B-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD32

Target Synonym: Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD32, FCG2, IGFR2,

Conjugation: Biotin

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Mouse IgG2b, κ

Clone No.: IV-3

UNIProt ID: P31994

Background: CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09813B

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 2212

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag