Product Description

Biotin Anti-Human CD35 Antibody [E11]

Size: 100μg

Catalogue Number: E-AB-F1062B-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD35

Target Synonym: Complement receptor type 1, CR1, C3b/C4b receptor, CD35, CR1, C3BR,

Conjugation: Biotin

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Mouse IgG1, κ

Clone No.: E11

UNIProt ID: P17927

Background: CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09793B

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 1378

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag