Biotin Anti-Human CD45RA Antibody (HI100)
Sizes: 25μg, 100μg
Catalogue Numbers: Biotin-30153U-25, Biotin-30153U-100
Citations, Manuals and MSDS Available upon request.
Target: Human CD45RA
Form: Liquid
Conjugation: Biotin
Host: Mouse
Clonality: Monoclonal
Clone ID: HI100
Isotype: IgG2b, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
Synonyms: CD45| L-CA| Ly-5| Ptprc| Receptor-type tyrosine-protein phosphatase C| T200
Uniprot ID: P08575
Reactivity: Human
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 5788
Category: Flow cytometryometry Antibodies
Research Use Only