Biotin Anti-Human CD45RA Antibody [HI100] - E-AB-F1052B

Biotin Anti-Human CD45RA Antibody [HI100]

Size: 100μg

Catalogue Number: E-AB-F1052B-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD45RA

Target Synonym: Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45,

Conjugation: Biotin

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Mouse IgG2b, κ

Clone No.: HI100

UNIProt ID: P08575

Background: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09813B

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 5788

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag