Biotin Anti-Human CD57 Antibody [HNK-1] - E-AB-F1067B

Biotin Anti-Human CD57 Antibody [HNK-1]

Size: 100μg

Catalogue Number: E-AB-F1067B-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD57

Target Synonym: HNK-1, NK-1, Leu-7,

Conjugation: Biotin

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Mouse IgM, κ

Clone No.: HNK-1

UNIProt ID: ???

Background: CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09783B

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 27087

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag