Product Description

Biotin Anti-Mouse CD120b/TNFR2 Antibody [TR75-54.7]

Size: 100μg

Catalogue Number: E-AB-F1035B-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD120b/TNFR2

Target Synonym: Tumor necrosis factor receptor superfamily member 1B, Tnfrsf1b, Tumor necrosis factor receptor 2, TNF-R2, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b,

Conjugation: Biotin

Host: Armenian Hamster

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Armenian Hamster IgG

Clone No.: TR75-54.7

UNIProt ID: P25119

Background: CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels, the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09853B

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 21938

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag