Biotin Anti-Mouse CD161/NK1.1 Antibody (PK136)
Sizes: 25μg, 100μg
Catalogue Numbers: Biotin-30029U-25, Biotin-30029U-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse CD161/NK1.1
Form: Liquid
Conjugation: Biotin
Host: Mouse
Clonality: Monoclonal
Clone ID: PK136
Isotype: IgG2a, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
Synonyms: CD161 antigen-like family member C| CD161| NK1.1| CD161c| Killer cell lectin-like receptor subfamily B member 1C| Klrb1c| Ly-55c| NKR-P1 40| NKR-P1.9| NKR-P1C
Uniprot ID: P27814, P27812, Q99JB4
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 17059
Category: Flow cytometryometry Antibodies
Research Use Only