Product Description

Biotin Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

Size: 100μg

Catalogue Number: E-AB-F1114B-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD183/CXCR3

Target Synonym: C-X-C chemokine receptor type 3, Cxcr3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor, CD183/CXCR3,

Conjugation: Biotin

Host: Armenian Hamster

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Armenian Hamster IgG

Clone No.: CXCR3-173

UNIProt ID: O88410

Background: CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09853B

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 12766

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag