Biotin Anti-Mouse CD80 Antibody (16-10A1)
Sizes: 25μg, 100μg
Catalogue Numbers: Biotin-30024U-25, Biotin-30024U-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse CD80
Form: Liquid
Conjugation: Biotin
Host: Armenian Hamster
Clonality: Monoclonal
Clone ID: 16-10A1
Isotype: IgG
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Synonyms: Activation B7-1 antigen| B7| Cd80| T-lymphocyte activation antigen CD80
Uniprot ID: Q00609
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 12519
Category: Flow cytometryometry Antibodies
Research Use Only