BLMH Polyclonal Antibody-BS6469

BLMH Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS6469-50, BS6469-100

Swiss-Prot: Q13867

Host: Rabbit

BLMH Polyclonal Antibody-BS6469

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

All Applications: WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:50

Background: BLM hydrolase (Bleomycin hydrolase, BLM hydrolase, BMH) is a 455 amino acid protein encoded by the human gene BLMH. BLM hydrolase belongs to the cysteine protease papain superfamily and the peptidase C1 family. It is a cytoplasmic cysteine peptidase commonly found as a homohexamer. It is highly conserved through evolution, however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM). BLM is an essential component of combination chemotherapy regimens for cancer.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: BLMH polyclonal antibody detects endogenous levels of BLMH protein.

Bioworld Molecular Weight: ~ 53 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using BLMH antibody., Immunofluorescence analysis of HeLa cell using BLMH antibody. Blue: DAPI for nuclear staining.

Alternative Name: Bleomycin hydrolase; BH; BLM hydrolase; BMH; BLMH

Immunogen: Recombinant full length Human BLMH.

Modification: Unmodified

Conjugate: Unconjugated