BMAL1 (phospho-Ser42) Rabbit Polyclonal Antibody - RA22426

BMAL1 (phospho-Ser42) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22426-50, RA22426-100

Citations, Manuals and MSDS Available upon request.

Background: aryl hydrocarbon receptor nuclear translocator like (ARNTL) Homo sapiens The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Basic-helix-loop-helix-PAS protein MOP3) (Brain and muscle ARNT-like 1) (Class E basic helix-loop-helix protein 5) (bHLHe5) (Member of PAS protein 3) (PAS domain-containing protein 3) (bHLH-PAS protein JAP3)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 406

Protein MW (KDa): 69

SWISS: O00327

Source: Rabbit

Research Use Only