BMI1 Polyclonal Antibody - E-AB-40381

BMI1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-40381-60, E-AB-40381-120, E-AB-40381-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: BMI1

Target Synonym: B lymphoma Mo MLV insertion region (mouse); B lymphoma Mo MLV insertion region 1 homolog; Bmi 1; BMI1; BMI1 polycomb ring finger oncogene; BMI1; Flvi 2/bmi 1; FLVI2/BMI1; MGC12685; Murine leukemia viral (bmi 1) oncogene homolog; Oncogene BMI 1; PCGF 4; PCGF4; Polycomb complex protein BMI 1; Polycomb complex protein BMI-1; Polycomb group protein Bmi1; Polycomb group ring finger 4; Polycomb group RING finger protein 4; RING finger protein 51; RNF 51; RNF51

Research Areas: Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells, Cancer

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P25916

Background: BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.

Concentration: 0.18mg/mL

Immunogen: Recombinant Mouse Polycomb complex protein BMI-1 protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification Method: Antigen Affinity Purification

Dilution: WB 1:500-1:1000

Calculated MW: 36 kDa

Observed MW: 36 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only