BMP-2 Polyclonal Antibody - BT-AP00920

BMP-2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00920-20, BT-AP00920-50, BT-AP00920-100

Citations, Manuals and MSDS Available upon request.

Background: BMP2 (bone morphogenetic protein 2) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of BMP2 causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

Research Areas: Cardiovascular

Target Protein: BMP2

Applications: IF, WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: BMP-2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 44702

UniProt Accession: Human: P12643; Mouse: P21274; Rat: P49001

Synonyms: BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A

GeneID: Human: 650; Mouse: 12156; Rat: 29373

Research Use Only