BMP-3 (E306) Polyclonal Antibody-BS3683

BMP-3 (E306) Polyclonal Antibody

Catalogue Numbers: BS3683-50, BS3683-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P12645

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB

All Applications: WB: 1:1000~1:2000

Background: Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: BMP-3 (E306) polyclonal antibody detects endogenous levels of BMP-3 protein.

Extra Notes: Western blot (WB) analysis of BMP-3 (E306) polyclonal antibody at 1:1000 dilution
Lane1:CT26 whole cell lysate(30ug)
Lane2:PC12 whole cell lysate(30ug)
Lane3:HepG2 whole cell lysate(30ug)
Lane4:A549 whole cell lysate(30ug

Bioworld Molecular Weight: ~ 56 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Bone morphogenetic protein 3; BMP-3; Bone morphogenetic protein 3A; BMP-3A; Osteogenin

Immunogen: Synthetic peptide, corresponding to Human BMP-3.

Conjugate: Unconjugated

Modification: Unmodified