Product Description

BMP-5 (L163) Polyclonal Antibody

Catalogue Numbers: BS3455-50, BS3455-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P22003

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1:2000~1:5000

Background: Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cartilage and bone formation or neurogenesis.Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2.In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.Can also signal through non-canonical pathway such as MAPK p38 signaling cascade to promote chondrogenic differentiation.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: BMP-5 (L163) polyclonal antibody detects endogenous levels of BMP-5 protein.

Extra Notes: Western blot (WB) analysis of BMP-5 (L163)polyclonal antibody at 1:2000 dilution
Lane1:EC9706 whole cell lysate(30ug)
Lane2:HCT116 whole cell lysate(30ug)
Lane3:A549 whole cell lysate(30ug)
Lane4:HEK293T whole cell lysate(30ug)

Bioworld Molecular Weight: ~ 53 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Bone morphogenetic protein 5; BMP-5

Immunogen: Synthetic peptide, corresponding to Human BMP-5.

Conjugate: Unconjugated

Modification: Unmodified