BMP-6 (A152) Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS3450-50, BS3450-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFβ receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adμlt organs. Category: Primary Antibody Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, IHC Alternate Names: Bone morphogenetic protein 6, BMP-6, VG-1-related protein (VG-1-R, VGR-1), BMP6, VGR Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodified Immunogen: A synthetic peptide of human BMP-6. Dilution: WB: 1:500~1:1000 IHC: 1:50~1:200 Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Specificity: BMP-6 (A152) polyclonal antibody detects endogenous levels of BMP-6 protein. Molecular Weight: ~ 55-65 kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: P22004 Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Research Use Only