BMP-7 Polyclonal Antibody - BT-AP00930

BMP-7 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00930-20, BT-AP00930-50, BT-AP00930-100

Citations, Manuals and MSDS Available upon request.

Background: BMP7 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients.

Research Areas: Signal Transduction

Target Protein: BMP7

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: BMP-7 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 49313

UniProt Accession: Human: P18075; Mouse: P23359

Synonyms: BMP7; OP1; Bone morphogenetic protein 7; BMP-7; Osteogenic protein 1; OP-1; Eptotermin alfa

GeneID: Human: 655; Mouse: 12162

Research Use Only