BMP4 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Number: BT-MCA3394-50, BT-MCA3394-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
Research Areas: Cancer, Stem cells, Cardiovascular, Signal transduction, Developmental biology
Target Protein: BMP4
Reactivity: Human
Clonality: Monoclonal
Clone ID: 10F4B4
Host: Mouse
Isotype: Mouse IgG1
Full Product Name: BMP4
Immunogen: Purified recombinant fragment of human BMP4 expressed in E. Coli.
Storage: 4°C|-20°C for long term storage
Formulation: Ascitic fluid containing 0.03% sodium azide.
Molecular Weight (Da): 64kDa
UniProt Accession: P12644
Synonyms: ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, BMP4
GeneID: 652
Research Use Only