BMPR-IB Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22448-50, RA22448-100
Citations, Manuals and MSDS Available upon request.
Background: bone morphogenetic protein receptor type 1B (BMPR1B) Homo sapiens This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for thi
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Alternative Names: Bone morphogenetic protein receptor type-1B (BMP type-1B receptor;BMPR-1B;EC 2.7.11.30;CD antigen CDw293)
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 658
SWISS: O00238
Source: Rabbit
Research Use Only