BMPR-IB rabbit pAb - ES8793

BMPR-IB rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8793-50, ES8793-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for thi

Alternate Name: Bone morphogenetic protein receptor type-1B (BMP type-1B receptor; BMPR-1B; EC 2.7.11.30; CD antigen CDw293)

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Reactivity: Human; Mouse

Immunogen: Synthetic peptide from human protein at AA range: 21-70

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 658

Human SWISS Prot NO: O00238

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only