BNP Monoclonal Antibody - BT-MCA2021

BNP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2021-50, BT-MCA2021-100

Citations, Manuals and MSDS Available upon request.

Background: BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.

Research Areas: Others

Target Protein: BNP

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8D5B4C11

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: BNP

Immunogen: Synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP, conjugated to KLH.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P16860

Synonyms: BNP, NPPB

GeneID: 4879

Research Use Only