Bob 1 rabbit pAb - ES8740

Bob 1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8740-50, ES8740-100

Citations, Manuals and MSDS Available upon request.

Background: disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t (3; 11) (q27; q23) with BCL6., function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers., PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation., similarity:Belongs to the POU2AF1 family., tissue specificity:B-cell specific.,

Alternate Name: POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1; BOB-1; OCA-B; OCT-binding factor 1)

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthetic peptide from human protein at AA range: 201-250

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 5450

Human SWISS Prot NO: Q16633

Subcellular Location: Nucleus

Research Use Only