BOD1 Polyclonal Antibody - E-AB-16283

BOD1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16283-60, E-AB-16283-120, E-AB-16283-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: BOD1

Target Synonym: Biorientation defective 1; Biorientation defective protein 1; biorientation of chromosomes in cell division 1; Biorientation of chromosomes in cell division protein 1; BOD1; BOD1; FAM44B; family with sequence similarity 44; member B; Protein FAM44B

Research Areas: Cell biology, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96IK1

Background: Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis.Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule-kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects.

Concentration: 0.7 mg/mL

Immunogen: Synthetic peptide of human BOD1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only