Product Description

BPI Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-14800-60, E-AB-14800-120, E-AB-14800-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: BPI

Target Synonym: Bactericidal permeability-increasing protein; Bactericidal/permeability increasing protein; BPI; BPI fold containing family D; member 1; BPI; BPIFD1; CAP 57; CAP57; rBPI; Recombinant BPI holoprotein; rBPI

Research Areas: Cardiovascular, Immunology, Microbiology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P17213

Background: This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

Concentration: 0.6 mg/mL

Immunogen: Recombinant protein of human BPI

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only