Bradykinin B1 R Polyclonal Antibody - BT-AP00963

Bradykinin B1 R Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP00963-20, BT-AP00963-50, BT-AP00963-100

Citations, Manuals and MSDS Available upon request.

Background: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by BDKRB1 (bradykinin receptor B1) is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for BDKRB1.

Research Areas: Immunology

Target Protein: BDKRB1

Applications: WB, IF, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Bradykinin B1 R Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 40495

UniProt Accession: Human: P46663; Mouse: Q61125

Synonyms: BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor

GeneID: Human: 623

Research Use Only