Product Description

BRAT1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10633-50, MB10633-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q6PJG6

Host: Rabbit

Reactivity: Human

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of BRAT1 in HCT116, HelaLysates using BRAT1 antibody.

Bioworld Molecular Weight: Calculated MW: 88 kDa; Observed MW: 88 kDa

Specificity: IgG

Alternative Name: BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1

Immunogen: Recombinant protein of human BRAT1

Conjugate: Unconjugated

Modification: Unmodified