Product Description

BRCAA1 (D810) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2935-50, BS2935-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The breast cancer-associated antigen BRCAA1, also designated ARID domaincontaining protein 4B (ARID4B), Sin3-associated polypeptide p180 (SAP180), or Retinoblastoma-binding protein 1-like 1 (RBBP1L1 or RBP1L1), shares 37% amino acid identity and an identical antigen epitope, SSKKQKRSHK, with Rb binding protein 1. High expression of BRCAA1 mRNA has been found in human breast, lung, colon, pancreatic and ovarian cancers, as well as in normal testis. This expression pattern indicates that BRCAA1 can be uses as a molecμlar marker for a broad range of human malignancies. BRCAA1 also interacts with RBBP1/ARID4A and regμlates genomic imprinting at the Prader-WIlli syndrome (PWS)/Angelman syndrome (AS) domain.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: AT-rich interactive domain-containing protein 4B, ARID domain-containing protein 4B, 180 kDa Sin3-associated polypeptide, Sin3-associated polypeptide p180, Breast cancer-associated antigen BRCAA1, Histone deacetylase complex subunit SAP180, Retinoblastoma-binding protein 1-like 1, ARID4B, BRCAA1, RBBP1L1, RBP1L1, SAP180

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 776-832 of Human BRCAA1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: BRCAA1 (D810) polyclonal antibody detects endogenous levels of BRCAA1 protein.

Molecular Weight: ~ 150 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q4LE39

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only